Lesson of Synthetic Epidemiology

Synthetic Epidemiology

Introduction: The role of ES is to explain the ED data using all the explanatory data provided by the EA and by the pathophysiology "the PA study" : Explain the data collected by the ED "such as the speed of propagation, incidence of a disease, ..." by using the data provided by the EA than by the explanations given by the physiopathological study of the PA . In order to do this, it responds to the questions raised by the ED, it reports to a significant effect that is significant for the population as a whole, it therefore calls for simplifications necessary for the establishment of a general law of the " The evolution of the disease in question and the understanding of reality " : We conclude from the data provided by the EA and ED the properties of a given disease such as: occurrence, factors of propagation, incidence, ... ".

The population at risk:

The character of the populations at risk and the morbidity and mortality results from three factors:

AP.

The receptivity of the exposed population.

Relation of the subject to the middle.

The PA: alone can be the eliment to explain the characteristics of the affected population, all of which have a pathogenic power whose support is complex, eg FA; MEM; .... The receptivity of AG may initially be due to the intrinsic natural receptivity proper to each animal species, depending on whether this animal species is receptive to any particular AP. The receptivity is defined at the molecular level by the fact that the species contains cell receptors allow the fixation of the AP, eg the equidae are not receptive to the boviseptic virus as well as BV.

For a given PA and a receptive species one can observe a receptive population and another that is not.

The host-environment relationship:

The host versus the environment: the host's relationship with his environment explains the exposure to risks by the place of residence and the activity.

Place of residence: eg BVs are more exposed to the risk of rabies contamination at pasture than in stalls "the same for dogs, therefore 95% of the dog's age is a companion".

The activity :

It can be behavior, eg: although the cat's population is half that of the dog, there are twice as many cases of rabies in this "feline" species, the cat is much less sedentary and its activities Nocturnes only lead the fox on the hunting ground.

The occupational activity "the exposed category": ex: leptospirosis especially strikes sewers, brucellosis mainly affects: veterinarians and breeders, butchers, ....

Leisure activities: also it allows to individualize a category of population, eg leptospirosis and bathers.

Place in relation to the host: a modification of the environment may modify the risk of exposure of a population, eg a very large decrease in the number of equidae leading to a change in the ecology of the mosquitoes Diseases »Zoophilia

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